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M3XZT7

Angiotensinogen (M3XZT7)

Uniprot ID M3XZT7
Protein Name Angiotensinogen
Gene Name AGT
Species Mustela putorius furo (European domestic ferret) (Mustela furo)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) Y Secretome P(b) 0.728
Function
GO - Molecular function
  • type 1 angiotensin receptor binding : IEA:Ensembl
  • type 2 angiotensin receptor binding : IEA:Ensembl
GO - Biological process
  • G-protein coupled receptor signaling pathway : IEA:Ensembl
  • kidney development : IEA:Ensembl
  • negative regulation of neurotrophin TRK receptor signaling pathway : IEA:Ensembl
  • positive regulation of activation of Janus kinase activity : IEA:Ensembl
  • positive regulation of branching involved in ureteric bud morphogenesis : IEA:Ensembl
  • positive regulation of cholesterol esterification : IEA:Ensembl
  • positive regulation of endothelial cell migration : IEA:Ensembl
  • positive regulation of epidermal growth factor receptor signaling pathway : IEA:Ensembl
  • positive regulation of extrinsic apoptotic signaling pathway : IEA:Ensembl
  • positive regulation of gap junction assembly : IEA:Ensembl
  • positive regulation of phosphatidylinositol 3-kinase signaling : IEA:Ensembl
  • positive regulation of protein tyrosine kinase activity : IEA:Ensembl
  • positive regulation of transcription, DNA-templated : IEA:Ensembl
  • regulation of cardiac conduction : IEA:Ensembl
  • regulation of extracellular matrix assembly : IEA:Ensembl
  • regulation of systemic arterial blood pressure by renin-angiotensin : IEA:InterPro
  • renal system process : IEA:Ensembl
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.