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M3XRN5

LDL receptor related protein 1 (M3XRN5)

Uniprot ID M3XRN5
Protein Name LDL receptor related protein 1
Gene Name LRP1
Species Mustela putorius furo (European domestic ferret) (Mustela furo)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) Y Secretome P(b) 0.0
Function
GO - Molecular function
  • alpha-2 macroglobulin receptor activity : IEA:Ensembl
  • apolipoprotein binding : IEA:Ensembl
  • calcium ion binding : IEA:InterPro
  • clathrin heavy chain binding : IEA:Ensembl
  • protein-containing complex binding : IEA:Ensembl
GO - Biological process
  • amyloid-beta clearance : IEA:Ensembl
  • astrocyte activation involved in immune response : IEA:Ensembl
  • cellular response to amyloid-beta : IEA:Ensembl
  • positive regulation of amyloid-beta clearance : IEA:Ensembl
  • positive regulation of cell death : IEA:Ensembl
  • positive regulation of endocytosis : IEA:Ensembl
  • positive regulation of lysosomal protein catabolic process : IEA:Ensembl
  • positive regulation of protein binding : IEA:Ensembl
  • positive regulation of protein localization to plasma membrane : IEA:Ensembl
  • transcytosis : IEA:Ensembl
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.