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140062

AMP deaminase 2 (Q01433)

Uniprot ID Q01433
Protein Name AMP deaminase 2
Gene Name AMPD2
Species Homo sapiens (Human)
Basic Information Experiments (0) Disease (0) Interactions
Signal peptide(a) N Secretome P(b)
Function AMP deaminase plays a critical role in energy metabolism. Catalyzes the deamination of AMP to IMP and plays an important role in the purine nucleotide cycle. .
GO - Molecular function
  • AMP deaminase activity : IGI:MGI
  • metal ion binding : IEA:UniProtKB-KW
GO - Biological process
  • cyclic purine nucleotide metabolic process : IMP:UniProtKB
  • energy homeostasis : IGI:MGI
  • IMP biosynthetic process : IGI:MGI
  • IMP salvage : IEA:UniProtKB-UniPathway
  • purine-containing compound salvage : TAS:Reactome
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.