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140056

Hemoglobin subunit alpha (P69905)

Uniprot ID P69905
Protein Name Hemoglobin subunit alpha
Gene Name HBA1
Species Homo sapiens (Human)
Basic Information Experiments (0) Disease (0) Interactions
Signal peptide(a) N Secretome P(b)
Function Involved in oxygen transport from the lung to the various peripheral tissues.
GO - Molecular function
  • heme binding : IBA:GO_Central
  • iron ion binding : IEA:InterPro
  • organic acid binding : IBA:GO_Central
  • oxygen binding : IBA:GO_Central
  • oxygen carrier activity : IBA:GO_Central
GO - Biological process
  • bicarbonate transport : TAS:Reactome
  • cellular oxidant detoxification : IEA:GOC
  • hydrogen peroxide catabolic process : IDA:BHF-UCL
  • oxygen transport : TAS:UniProtKB
  • positive regulation of cell death : IDA:BHF-UCL
  • receptor-mediated endocytosis : TAS:Reactome
  • response to hydrogen peroxide : IDA:BHF-UCL
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.