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140037

Lumican (P51884)

Uniprot ID P51884
Protein Name Lumican
Gene Name LUM
Species Homo sapiens (Human)
Basic Information Experiments (0) Disease (0) Interactions
Signal peptide(a) Y Secretome P(b)
Function
GO - Molecular function
  • collagen binding : IDA:UniProtKB
  • extracellular matrix structural constituent : NAS:UniProtKB
GO - Biological process
  • cartilage development : IEA:Ensembl
  • collagen fibril organization : NAS:UniProtKB
  • extracellular matrix organization : TAS:Reactome
  • keratan sulfate biosynthetic process : TAS:Reactome
  • keratan sulfate catabolic process : TAS:Reactome
  • positive regulation of transcription by RNA polymerase II : IEA:Ensembl
  • positive regulation of transforming growth factor beta1 production : IEA:Ensembl
  • response to growth factor : IEA:Ensembl
  • response to organic cyclic compound : IEA:Ensembl
  • visual perception : TAS:ProtInc
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.