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140007

Transketolase (P29401)

Uniprot ID P29401
Protein Name Transketolase
Gene Name TKT
Species Homo sapiens (Human)
Basic Information Experiments (0) Disease (0) Interactions
Signal peptide(a) N Secretome P(b)
Function Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. .
GO - Molecular function
  • cofactor binding : IDA:UniProtKB
  • metal ion binding : IEA:UniProtKB-KW
  • protein homodimerization activity : IDA:UniProtKB
  • transketolase activity : IDA:UniProtKB
GO - Biological process
  • glyceraldehyde-3-phosphate biosynthetic process : IDA:UniProtKB
  • pentose-phosphate shunt : TAS:Reactome
  • pentose-phosphate shunt, non-oxidative branch : NAS:UniProtKB
  • regulation of growth : IEA:Ensembl
  • xylulose biosynthetic process : TAS:Reactome
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.