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139998

Alanine aminotransferase 1 (P24298)

Uniprot ID P24298
Protein Name Alanine aminotransferase 1
Gene Name GPT
Species Homo sapiens (Human)
Basic Information Experiments (0) Disease (0) Interactions
Signal peptide(a) N Secretome P(b)
Function Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. Participates in cellular nitrogen metabolism and also in liver gluconeogenesis starting with precursors transported from skeletal muscles (By similarity). .
GO - Molecular function
  • L-alanine : EXP:Reactome
  • pyridoxal phosphate binding : IEA:InterPro
GO - Biological process
  • cellular amino acid biosynthetic process : TAS:Reactome
  • L-alanine catabolic process : IEA:UniProtKB-UniPathway
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.