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139997

Peptidyl-prolyl cis-trans isomerase B (P23284)

Uniprot ID P23284
Protein Name Peptidyl-prolyl cis-trans isomerase B
Gene Name PPIB
Species Homo sapiens (Human)
Basic Information Experiments (0) Disease (0) Interactions
Signal peptide(a) Y Secretome P(b)
Function PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. .
GO - Molecular function
  • cyclosporin A binding : IDA:UniProtKB
  • peptidyl-prolyl cis-trans isomerase activity : IDA:UniProtKB
  • protein-containing complex binding : ISS:UniProtKB
  • RNA binding : HDA:UniProtKB
  • RNA polymerase binding : IPI:AgBase
  • unfolded protein binding : TAS:ProtInc
GO - Biological process
  • bone development : IMP:UniProtKB
  • chaperone-mediated protein folding : IDA:UniProtKB
  • positive regulation by host of viral genome replication : IMP:AgBase
  • positive regulation by host of viral process : IMP:AgBase
  • positive regulation of multicellular organism growth : IMP:UniProtKB
  • protein peptidyl-prolyl isomerization : IDA:UniProtKB
  • protein stabilization : IMP:UniProtKB
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.