Alpha-N-acetylgalactosaminidase (P17050)

Uniprot ID P17050
Protein Name Alpha-N-acetylgalactosaminidase
Gene Name NAGA
Species Homo sapiens (Human)
Signal peptide(a) Y Secretome P(b)
Function Removes terminal alpha-N-acetylgalactosamine residues from glycolipids and glycopeptides. Required for the breakdown of glycolipids. .
GO - Molecular function
  • alpha-galactosidase activity : IBA:GO_Central
  • alpha-N-acetylgalactosaminidase activity : IDA:UniProtKB
  • protein homodimerization activity : IPI:UniProtKB
GO - Biological process
  • carbohydrate catabolic process : IDA:UniProtKB
  • glycolipid catabolic process : IMP:UniProtKB
  • glycoside catabolic process : IBA:GO_Central
  • glycosylceramide catabolic process : IBA:GO_Central
  • oligosaccharide metabolic process : IBA:GO_Central
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.