Fatty acid-binding protein, adipocyte (P15090)

Uniprot ID P15090
Protein Name Fatty acid-binding protein, adipocyte
Gene Name FABP4
Species Homo sapiens (Human)
Signal peptide(a) N Secretome P(b)
Function Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus. .
GO - Molecular function
  • fatty acid binding : TAS:ProtInc
GO - Biological process
  • brown fat cell differentiation : IEA:Ensembl
  • cellular response to lithium ion : IEA:Ensembl
  • cellular response to tumor necrosis factor : IEA:Ensembl
  • cholesterol homeostasis : IEA:Ensembl
  • cytokine production : IEA:Ensembl
  • negative regulation of protein kinase activity : IEA:Ensembl
  • negative regulation of transcription, DNA-templated : IEA:Ensembl
  • positive regulation of inflammatory response : IEA:Ensembl
  • triglyceride catabolic process : TAS:Reactome
  • white fat cell differentiation : IEA:Ensembl
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.