| Signal peptide(a) |
N |
Secretome P(b) |
|
| Function |
Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen. . |
| GO - Molecular function |
- catalytic activity : TAS:ProtInc
- identical protein binding : IPI:UniProtKB
- porphobilinogen synthase activity : IDA:UniProtKB
- proteasome core complex binding : IEA:Ensembl
- zinc ion binding : IDA:UniProtKB
|
| GO - Biological process |
- cellular response to interleukin-4 : IEA:Ensembl
- cellular response to lead ion : IEA:Ensembl
- heme biosynthetic process : IDA:UniProtKB
- negative regulation of proteasomal protein catabolic process : IDA:CAFA
- neutrophil degranulation : TAS:Reactome
- protein homooligomerization : IPI:UniProtKB
- protoporphyrinogen IX biosynthetic process : IEA:UniProtKB-UniPathway
- response to activity : IEA:Ensembl
- response to aluminum ion : IEA:Ensembl
- response to amino acid : IEA:Ensembl
- response to arsenic-containing substance : IEA:Ensembl
- response to cadmium ion : IEA:Ensembl
- response to cobalt ion : IEA:Ensembl
- response to ethanol : IEA:Ensembl
- response to fatty acid : IEA:Ensembl
- response to glucocorticoid : IEA:Ensembl
- response to herbicide : IEA:Ensembl
- response to hypoxia : IEA:Ensembl
- response to ionizing radiation : IEA:Ensembl
- response to iron ion : IEA:Ensembl
- response to lipopolysaccharide : IEA:Ensembl
- response to mercury ion : IEA:Ensembl
- response to methylmercury : IEA:Ensembl
- response to oxidative stress : IEA:Ensembl
- response to platinum ion : IEA:Ensembl
- response to selenium ion : IEA:Ensembl
- response to vitamin B1 : IEA:Ensembl
- response to vitamin E : IEA:Ensembl
- response to zinc ion : IEA:Ensembl
|