Translationally-controlled tumor protein (P13693)

Uniprot ID P13693
Protein Name Translationally-controlled tumor protein
Gene Name TPT1
Species Homo sapiens (Human)
Signal peptide(a) N Secretome P(b)
Function Involved in calcium binding and microtubule stabilization.
GO - Molecular function
  • calcium ion binding : IDA:UniProtKB
  • RNA binding : HDA:UniProtKB
GO - Biological process
  • calcium ion transport : IC:UniProtKB
  • cellular calcium ion homeostasis : IC:UniProtKB
  • negative regulation of apoptotic process : TAS:UniProtKB
  • negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage : IMP:MGI
  • regulation of apoptotic process : NAS:UniProtKB
  • response to virus : IEP:UniProtKB
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.