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139960

Beta-glucuronidase (P08236)

Uniprot ID P08236
Protein Name Beta-glucuronidase
Gene Name GUSB
Species Homo sapiens (Human)
Basic Information Experiments (0) Disease (0) Interactions
Signal peptide(a) Y Secretome P(b)
Function Plays an important role in the degradation of dermatan and keratan sulfates.
GO - Molecular function
  • beta-glucuronidase activity : TAS:Reactome
  • hydrolase activity, hydrolyzing O-glycosyl compounds : IBA:GO_Central
  • protein domain specific binding : IPI:AgBase
  • signaling receptor binding : IPI:AgBase
GO - Biological process
  • carbohydrate metabolic process : TAS:ProtInc
  • glycosaminoglycan catabolic process : TAS:Reactome
  • hyaluronan catabolic process : TAS:Reactome
  • neutrophil degranulation : TAS:Reactome
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.