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139956

Alpha-galactosidase A (P06280)

Uniprot ID P06280
Protein Name Alpha-galactosidase A
Gene Name GLA
Species Homo sapiens (Human)
Basic Information Experiments (0) Disease (0) Interactions
Signal peptide(a) Y Secretome P(b)
Function
GO - Molecular function
  • alpha-galactosidase activity : IDA:UniProtKB
  • catalytic activity : IDA:UniProtKB
  • galactoside binding : IEA:Ensembl
  • hydrolase activity : TAS:UniProtKB
  • protein homodimerization activity : IDA:UniProtKB
  • raffinose alpha-galactosidase activity : IEA:UniProtKB-EC
  • signaling receptor binding : IDA:UniProtKB
GO - Biological process
  • glycoside catabolic process : IBA:GO_Central
  • glycosphingolipid catabolic process : TAS:UniProtKB
  • glycosphingolipid metabolic process : TAS:Reactome
  • glycosylceramide catabolic process : ISS:UniProtKB
  • negative regulation of nitric oxide biosynthetic process : ISS:UniProtKB
  • negative regulation of nitric-oxide synthase activity : ISS:UniProtKB
  • neutrophil degranulation : TAS:Reactome
  • oligosaccharide metabolic process : IDA:UniProtKB
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.