| Signal peptide(a) |
N |
Secretome P(b) |
|
| Function |
Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells. . |
| GO - Molecular function |
- aminoacylase activity : IEA:Ensembl
- antioxidant activity : IDA:UniProtKB
- catalase activity : IDA:UniProtKB
- enzyme binding : IPI:UniProtKB
- heme binding : IDA:UniProtKB
- identical protein binding : IPI:IntAct
- metal ion binding : IEA:UniProtKB-KW
- NADP binding : IDA:UniProtKB
- oxidoreductase activity, acting on peroxide as acceptor : ISS:UniProtKB
- protein homodimerization activity : IDA:UniProtKB
- signaling receptor binding : IPI:UniProtKB
|
| GO - Biological process |
- aerobic respiration : IEA:Ensembl
- aging : IEA:Ensembl
- cellular response to growth factor stimulus : IEA:Ensembl
- cellular response to oxidative stress : TAS:Reactome
- cholesterol metabolic process : IEA:Ensembl
- hemoglobin metabolic process : IEA:Ensembl
- hydrogen peroxide catabolic process : IDA:UniProtKB
- negative regulation of apoptotic process : IMP:UniProtKB
- negative regulation of NF-kappaB transcription factor activity : IEA:Ensembl
- neutrophil degranulation : TAS:Reactome
- osteoblast differentiation : HDA:UniProtKB
- positive regulation of cell division : IEA:UniProtKB-KW
- positive regulation of NF-kappaB transcription factor activity : IEA:Ensembl
- positive regulation of phosphatidylinositol 3-kinase signaling : IEA:Ensembl
- protein homotetramerization : IDA:UniProtKB
- protein targeting to peroxisome : TAS:Reactome
- protein tetramerization : IDA:UniProtKB
- response to activity : IEA:Ensembl
- response to cadmium ion : IEA:Ensembl
- response to estradiol : IEA:Ensembl
- response to ethanol : IEA:Ensembl
- response to fatty acid : IEA:Ensembl
- response to hydrogen peroxide : IBA:GO_Central
- response to hyperoxia : IEA:Ensembl
- response to hypoxia : IEA:Ensembl
- response to inactivity : IEA:Ensembl
- response to insulin : IEA:Ensembl
- response to L-ascorbic acid : IEA:Ensembl
- response to lead ion : IEA:Ensembl
- response to light intensity : IEA:Ensembl
- response to ozone : IEA:Ensembl
- response to phenylpropanoid : IEA:Ensembl
- response to reactive oxygen species : IMP:UniProtKB
- response to vitamin A : IEA:Ensembl
- response to vitamin E : IEA:Ensembl
- triglyceride metabolic process : IEA:Ensembl
- ureteric bud development : IEA:Ensembl
- UV protection : IMP:UniProtKB
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