| Signal peptide(a) |
N |
Secretome P(b) |
|
| Function |
Essential for bone resorption and osteoclast differentiation (By similarity). Reversible hydration of carbon dioxide. Can hydrate cyanamide to urea. Involved in the regulation of fluid secretion into the anterior chamber of the eye. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6. . |
| GO - Molecular function |
- arylesterase activity : IMP:CACAO
- carbonate dehydratase activity : IMP:CACAO
- zinc ion binding : IDA:UniProtKB
|
| GO - Biological process |
- angiotensin-activated signaling pathway : IDA:UniProtKB
- bicarbonate transport : TAS:Reactome
- carbon dioxide transport : IEA:Ensembl
- cellular response to fluid shear stress : IEA:Ensembl
- kidney development : IEA:Ensembl
- morphogenesis of an epithelium : IEA:Ensembl
- odontogenesis of dentin-containing tooth : IEA:Ensembl
- positive regulation of bone resorption : IEA:Ensembl
- positive regulation of cellular pH reduction : IEA:Ensembl
- positive regulation of dipeptide transmembrane transport : ISS:UniProtKB
- positive regulation of osteoclast differentiation : IEA:Ensembl
- positive regulation of synaptic transmission, GABAergic : IEA:Ensembl
- regulation of anion transport : IDA:UniProtKB
- regulation of chloride transport : IEA:Ensembl
- regulation of intracellular pH : ISS:UniProtKB
- response to estrogen : IEA:Ensembl
- response to pH : IEA:Ensembl
- response to steroid hormone : IEA:Ensembl
- response to zinc ion : IEA:Ensembl
- secretion : IEA:Ensembl
|