Signal peptide(a) |
N |
Secretome P(b) |
|
Function |
Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids. . |
GO - Molecular function |
- 4-hydroxyglutamate transaminase activity : TAS:Reactome
- amino acid binding : IEA:Ensembl
- enzyme binding : IEA:Ensembl
- kynurenine-oxoglutarate transaminase activity : IEA:UniProtKB-EC
- L-aspartate : IDA:UniProtKB
- phospholipid binding : IEA:Ensembl
- protein homodimerization activity : IEA:Ensembl
- pyridoxal phosphate binding : IEA:Ensembl
- RNA binding : HDA:UniProtKB
|
GO - Biological process |
- 2-oxoglutarate metabolic process : ISS:UniProtKB
- 4-hydroxyproline catabolic process : TAS:BHF-UCL
- aspartate biosynthetic process : IEA:Ensembl
- aspartate catabolic process : IDA:UniProtKB
- aspartate metabolic process : ISS:UniProtKB
- cellular amino acid biosynthetic process : TAS:Reactome
- fatty acid transport : IEP:UniProtKB
- female pregnancy : IEA:Ensembl
- gluconeogenesis : TAS:Reactome
- glutamate catabolic process to 2-oxoglutarate : IEA:Ensembl
- glutamate catabolic process to aspartate : IEA:Ensembl
- glutamate metabolic process : ISS:UniProtKB
- glyoxylate metabolic process : TAS:Reactome
- lactation : IEA:Ensembl
- oxaloacetate metabolic process : IEA:Ensembl
- response to ethanol : IDA:UniProtKB
- response to insulin : IEA:Ensembl
- response to morphine : IEA:Ensembl
- response to muscle activity : IEA:Ensembl
|