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139925

Phosphomannomutase 2 (O15305)

Uniprot ID O15305
Protein Name Phosphomannomutase 2
Gene Name PMM2
Species Homo sapiens (Human)
Basic Information Experiments (0) Disease (0) Interactions
Signal peptide(a) N Secretome P(b)
Function Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. .
GO - Molecular function
  • phosphomannomutase activity : IBA:GO_Central
GO - Biological process
  • GDP-mannose biosynthetic process : TAS:Reactome
  • mannose metabolic process : IBA:GO_Central
  • protein glycosylation : TAS:ProtInc
  • protein N-linked glycosylation : IBA:GO_Central
  • protein targeting to ER : IBA:GO_Central
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.