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12238

Netrin-4 (Q9HB63)

Uniprot ID Q9HB63
Protein Name Netrin-4
Gene Name NTN4
Species Homo sapiens (Human)
Basic Information Experiments (2) Disease (0) Interactions
Signal peptide(a) N Secretome P(b) 0.37
Function May play an important role in neural, kidney and vascular development. Promotes neurite elongation from olfactory bulb explants. .
GO - Molecular function
  • laminin-1 binding : IEA:Ensembl
GO - Biological process
  • animal organ morphogenesis : IBA:GO_Central
  • axon guidance : TAS:Reactome
  • basement membrane assembly : IBA:GO_Central
  • cell migration : IBA:GO_Central
  • neuron remodeling : IEA:Ensembl
  • regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling : IEA:Ensembl
  • substrate adhesion-dependent cell spreading : IBA:GO_Central
  • tissue development : IBA:GO_Central
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.