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12234

Protein tweety homolog 1 (Q9H313)

Uniprot ID Q9H313
Protein Name Protein tweety homolog 1
Gene Name TTYH1
Species Homo sapiens (Human)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) N Secretome P(b) 0.162
Function Probable chloride channel. May be involved in cell adhesion (By similarity). .Isoform 3 may be a Ca(2+)-independent and swelling-activated chloride channel, possibly involved in regulation of cell volume.
GO - Molecular function
  • calcium ion binding : IEA:Ensembl
  • chloride channel activity : TAS:Reactome
  • intracellular calcium activated chloride channel activity : IBA:GO_Central
  • iron ion transmembrane transporter activity : NAS:UniProtKB
  • volume-sensitive chloride channel activity : IDA:FlyBase
GO - Biological process
  • cell-cell adhesion : IEA:Ensembl
  • cell-substrate adhesion : IEA:Ensembl
  • chloride transport : IDA:FlyBase
  • filopodium assembly : IEA:Ensembl
  • ion transmembrane transport : TAS:Reactome
  • iron ion transport : NAS:UniProtKB
  • mitotic cell cycle : IEA:Ensembl
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.