Home Proteins Experiments Diseases Interactions Tutorial
Home
/
Proteins
/
11253

Insulin-like growth factor-binding protein 7 (Q16270)

Uniprot ID Q16270
Protein Name Insulin-like growth factor-binding protein 7
Gene Name IGFBP7
Species Homo sapiens (Human)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) Y Secretome P(b) 0.555
Function Binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion. .
GO - Molecular function
  • insulin-like growth factor binding : IEA:InterPro
GO - Biological process
  • cell adhesion : IDA:UniProtKB
  • cellular protein metabolic process : TAS:Reactome
  • cellular response to hormone stimulus : IEA:Ensembl
  • embryo implantation : IEA:Ensembl
  • negative regulation of cell proliferation : TAS:ProtInc
  • post-translational protein modification : TAS:Reactome
  • regulation of cell growth : IEA:InterPro
  • regulation of steroid biosynthetic process : IEA:Ensembl
  • response to cortisol : IEA:Ensembl
  • response to heat : IEA:Ensembl
  • response to retinoic acid : IEA:Ensembl
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.