Home Proteins Experiments Diseases Interactions Tutorial
Home
/
Proteins
/
11244

Calponin-3 (Q15417)

Uniprot ID Q15417
Protein Name Calponin-3
Gene Name CNN3
Species Homo sapiens (Human)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) N Secretome P(b) 0.739
Function Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.
GO - Molecular function
  • actin binding : IEA:UniProtKB-KW
  • cadherin binding involved in cell-cell adhesion : HDA:BHF-UCL
  • calmodulin binding : IEA:UniProtKB-KW
  • microtubule binding : IEA:Ensembl
GO - Biological process
  • actomyosin structure organization : IEA:InterPro
  • epithelial cell differentiation : IEP:UniProtKB
  • negative regulation of ATPase activity : IEA:Ensembl
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.