| Signal peptide(a) |
Y |
Secretome P(b) |
0.712 |
| Function |
Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization (By similarity). Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. .Medin is the main constituent of aortic medial amyloid. {ECO:0000269|PubMed:19204935}. |
| GO - Molecular function |
- integrin binding : IEA:Ensembl
- phosphatidylethanolamine binding : IEA:Ensembl
- phosphatidylserine binding : IEA:Ensembl
|
| GO - Biological process |
- angiogenesis : IEA:UniProtKB-KW
- apoptotic cell clearance : IEA:Ensembl
- cell adhesion : IEA:UniProtKB-KW
- cellular protein metabolic process : TAS:Reactome
- phagocytosis, engulfment : IEA:Ensembl
- phagocytosis, recognition : IEA:Ensembl
- positive regulation of phagocytosis : IEA:Ensembl
- post-translational protein modification : TAS:Reactome
- single fertilization : IEA:UniProtKB-KW
- viral process : IEA:UniProtKB-KW
|