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10958

Glia maturation factor beta (P60983)

Uniprot ID P60983
Protein Name Glia maturation factor beta
Gene Name GMFB
Species Homo sapiens (Human)
Basic Information Experiments (2) Disease (0) Interactions
Signal peptide(a) N Secretome P(b) 0.879
Function This protein causes differentiation of brain cells, stimulation of neural regeneration, and inhibition of proliferation of tumor cells.
GO - Molecular function
  • actin binding : IEA:InterPro
  • Arp2/3 complex binding : IEA:InterPro
  • enzyme activator activity : TAS:ProtInc
  • growth factor activity : IEA:UniProtKB-KW
  • protein kinase inhibitor activity : TAS:ProtInc
GO - Biological process
  • learning : IEA:Ensembl
  • locomotory behavior : IEA:Ensembl
  • negative regulation of Arp2/3 complex-mediated actin nucleation : IEA:InterPro
  • nervous system development : TAS:ProtInc
  • protein phosphorylation : TAS:ProtInc
  • signal transduction : TAS:ProtInc
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.