Gliome Database

Protein Name	Gene Name	Uniprot ID	Disease Name	References
Heparan sulfate proteoglycan 2	HSPG2	M3YX39	Alzheimer's Disease	Iivonen, S. et al. (Neurosci Lett, 2003) and 3 others Iivonen, S. et al. (Neurosci Lett, 2003), Rosenmann, H. et al. (Am J Med Genet B Neuropsychiatr Genet, 2004), Wang, B. et al. (Dement Geriatr Cogn Disord, 2007), van Duinen, S. G. et al. (Lab Invest, 1995)
Basement membrane-specific heparan sulfate proteoglycan core protein	Hspg2	Q05793	Alzheimer's Disease	Iivonen, S. et al. (Neurosci Lett, 2003) and 3 others Iivonen, S. et al. (Neurosci Lett, 2003), Rosenmann, H. et al. (Am J Med Genet B Neuropsychiatr Genet, 2004), Wang, B. et al. (Dement Geriatr Cogn Disord, 2007), van Duinen, S. G. et al. (Lab Invest, 1995)
Low-density lipoprotein receptor-related protein 2	Lrp2	A2ARV4	Alzheimer's Disease	Schnurra, I. et al. (Neurobiol Dis, 2001) and 3 others Schnurra, I. et al. (Neurobiol Dis, 2001), Vargas, T. et al. (Am J Med Genet B Neuropsychiatr Genet, 2010), Wang, L. L. et al. (Clin Chim Acta, 2011), Dietrich, M. et al. (J Alzheimers Dis, 2014)
Protein SET	Set	Q9EQU5	Alzheimer's Disease	Wang, X. et al. (FASEB J, 2010) and 2 others Wang, X. et al. (FASEB J, 2010), Yu, G. et al. (Neurobiol Aging, 2013), Facchinetti, P. et al. (Neurobiol Aging, 2014)
Lactoylglutathione lyase	Glo1	Q9CPU0	Alzheimer's Disease	Chen, F. et al. (Proc Natl Acad Sci U S A, 2004), Nerl, C. et al. (Neurology, 1984)
Lactoylglutathione lyase	Glo1	Q6P7Q4	Alzheimer's Disease	Chen, F. et al. (Proc Natl Acad Sci U S A, 2004), Nerl, C. et al. (Neurology, 1984)
Synaptic functional regulator FMR1	Fmr1	P35922	Alzheimer's Disease	Hall, D. A. et al. (Neurobiol Aging, 2014)
Lactadherin	Mfge8	P21956	Alzheimer's Disease	Fuller, A. D. et al. (J Neuroimmune Pharmacol, 2008)
Lactadherin	Mfge8	P70490	Alzheimer's Disease	Fuller, A. D. et al. (J Neuroimmune Pharmacol, 2008)
Platelet-activating factor acetylhydrolase	Pla2g7	Q60963	Alzheimer's Disease	Koshy, B. et al. (J Alzheimers Dis, 2010) and 2 others Koshy, B. et al. (J Alzheimers Dis, 2010), van Himbergen, T. M. et al. (Arch Neurol, 2012), Bacchetti, T. et al. (J Alzheimers Dis, 2015)
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Pin1	Q9QUR7	Alzheimer's Disease	Wulf, G. M. et al. (EMBO J, 2001) and 30 others Wulf, G. M. et al. (EMBO J, 2001), Hamdane, M. et al. (J Mol Neurosci, 2002), Miyashita, H. et al. (Oncol Rep, 2003), Liou, Y. C. et al. (Nature, 2003), Ramakrishnan, P. et al. (Neurobiol Dis, 2003), Sultana, R. et al. (Neurobiol Aging, 2006), Poli, M. et al. (Neurosci Lett, 2005), Segat, L. et al. (Neurobiol Aging, 2007), Pastorino, L. et al. (Nature, 2006), Hamdane, M. et al. (Mol Cell Neurosci, 2006), Lambert, J. C. et al. (Neurosci Lett, 2006), Butterfield, D. A. et al. (J Neurochem, 2006), Balastik, M. et al. (Biochim Biophys Acta, 2007), Wang, S. et al. (J Alzheimers Dis, 2007), Takahashi, K. et al. (Cell Mol Life Sci, 2008), Arosio, B. et al. (Aging Clin Exp Res, 2007), Rudrabhatla, P. et al. (J Biol Chem, 2008), Behrens, M. I. et al. (Curr Alzheimer Res, 2009), Maruszak, A. et al. (BMC Med Genet, 2009), Rudrabhatla, P. et al. (J Neurosci, 2009), Hall, E. C. 2nd et al. (Biochim Biophys Acta, 2010), Rudrabhatla, P. et al. (J Alzheimers Dis, 2010), Ma, S. L. et al. (Neurobiol Aging, 2012), Dakson, A. et al. (Acta Neuropathol, 2011), Ma, S. L. et al. (J Biol Chem, 2012), Arosio, B. et al. (Neurodegener Dis, 2012), Cao, L. et al. (Neurosci Lett, 2013), Wang, J. Z. et al. (J Inorg Biochem, 2013), Driver, J. A. et al. (Biochim Biophys Acta, 2015), Ferri, E. et al. (J Neurol Sci, 2016), Xu, L. et al. (Neural Plast, 2017)
Eukaryotic translation initiation factor 4E-binding protein 1	Eif4ebp1	Q60876	Alzheimer's Disease	Li, X. et al. (FEBS J, 2005)
Bleomycin hydrolase	Blmh	Q8R016	Alzheimer's Disease	Shastry, B. S. et al. (Brain Res Bull, 1999) and 8 others Shastry, B. S. et al. (Brain Res Bull, 1999), Raina, A. K. et al. (Neuroreport, 1999), Thome, J. et al. (Neurosci Lett, 1999), Papassotiropoulos, A. et al. (Mol Psychiatry, 2000), Hu, C. J. et al. (J Neurol Sci, 2000), Nivet-Antoine, V. et al. (Ann Biol Clin (Paris), 2003), Smach, M. A. et al. (Neurol Sci, 2010), Suszynska, J. et al. (J Alzheimers Dis, 2010), Farrer, L. A. et al. (Ann Neurol, 1998)
Bleomycin hydrolase	Blmh	P70645	Alzheimer's Disease	Shastry, B. S. et al. (Brain Res Bull, 1999) and 8 others Shastry, B. S. et al. (Brain Res Bull, 1999), Raina, A. K. et al. (Neuroreport, 1999), Thome, J. et al. (Neurosci Lett, 1999), Papassotiropoulos, A. et al. (Mol Psychiatry, 2000), Hu, C. J. et al. (J Neurol Sci, 2000), Nivet-Antoine, V. et al. (Ann Biol Clin (Paris), 2003), Smach, M. A. et al. (Neurol Sci, 2010), Suszynska, J. et al. (J Alzheimers Dis, 2010), Farrer, L. A. et al. (Ann Neurol, 1998)
Inactive phospholipase C-like protein 1	Plcl1	Q3USB7	Alzheimer's Disease	Schellenberg, G. D. et al. (Am J Hum Genet, 1991)
Insulin-like growth factor-binding protein 7	Igfbp7	Q61581	Alzheimer's Disease	Agbemenyah, H. Y. et al. (Neurobiol Dis, 2014)
Ceramide glucosyltransferase	Ugcg	O88693	Alzheimer's Disease	Marks, N. et al. (Brain Res, 2008), Grimm, M. O. et al. (Cell Physiol Biochem, 2014)
Glutaminyl-peptide cyclotransferase	Qpct	Q9CYK2	Alzheimer's Disease	Hook, V. et al. (Biol Chem, 2008) and 5 others Hook, V. et al. (Biol Chem, 2008), Jawhar, S. et al. (J Biol Chem, 2011), Hartlage-Rubsamen, M. et al. (Acta Neuropathol, 2011), De Kimpe, L. et al. (PLoS One, 2012), Valenti, M. T. et al. (J Alzheimers Dis, 2013), Morawski, M. et al. (J Alzheimers Dis, 2014)
Macrophage-expressed gene 1 protein	Mpeg1	A1L314	Alzheimer's Disease	Unger, T. et al. (Am J Geriatr Psychiatry, 2005)
5'-3' exonuclease PLD3	Pld3	Q5FVH2	Alzheimer's Disease	Cruchaga, C. et al. (Nature, 2014) and 5 others Cruchaga, C. et al. (Nature, 2014), Jiao, B. et al. (Neurobiol Aging, 2014), Wang, J. et al. (Mol Neurobiol, 2015), Wang, C. et al. (J Alzheimers Dis, 2015), Cacace, R. et al. (Hum Mutat, 2015), Lin, E. et al. (Oncotarget, 2017)
Multiple epidermal growth factor-like domains protein 10	Megf10	Q6DIB5	Alzheimer's Disease	Singh, T. D. et al. (FEBS Lett, 2010), Sherva, R. et al. (Alzheimers Dement, 2014)
Sortilin	Sort1	O54861	Alzheimer's Disease	Finan, G. M. et al. (J Biol Chem, 2011) and 5 others Finan, G. M. et al. (J Biol Chem, 2011), Wang, H. F. et al. (Brain Res, 2012), Reynolds, C. A. et al. (Neurobiol Aging, 2013), Reitz, C. et al. (Transl Psychiatry, 2013), Saadipour, K. et al. (J Neurochem, 2013), Huang, C. C. et al. (Sci Rep, 2016)
Aconitate hydratase, mitochondrial	Aco2	Q99KI0	Alzheimer's Disease	Raukas, M. et al. (Free Radic Res, 2012)
Netrin-4	Ntn4	Q9JI33	Alzheimer's Disease	Saad, M. et al. (Genes Brain Behav, 2015)
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1	Pag1	Q3U1F9	Alzheimer's Disease	Caccamo, A. et al. (Proc Natl Acad Sci U S A, 2010) and 3 others Caccamo, A. et al. (Proc Natl Acad Sci U S A, 2010), Liu, R. et al. (Neurobiol Dis, 2012), Moon, M. et al. (J Alzheimers Dis, 2012), Song, H. et al. (Mol Neurodegener, 2015)

HSPG2

Alzheimer's Disease

Iivonen, S. et al. (Neurosci Lett, 2003) and 3 others

Iivonen, S. et al. (Neurosci Lett, 2003), Rosenmann, H. et al. (Am J Med Genet B Neuropsychiatr Genet, 2004), Wang, B. et al. (Dement Geriatr Cogn Disord, 2007), van Duinen, S. G. et al. (Lab Invest, 1995)

Basement membrane-specific heparan sulfate proteoglycan core protein

Hspg2

Q05793

Alzheimer's Disease

Iivonen, S. et al. (Neurosci Lett, 2003) and 3 others

Iivonen, S. et al. (Neurosci Lett, 2003), Rosenmann, H. et al. (Am J Med Genet B Neuropsychiatr Genet, 2004), Wang, B. et al. (Dement Geriatr Cogn Disord, 2007), van Duinen, S. G. et al. (Lab Invest, 1995)

Low-density lipoprotein receptor-related protein 2

Lrp2