Gliome Database

Protein Name	Gene Name	Uniprot ID	Disease Name	References
Apolipoprotein E	Apoe	P08226	Amyotrophic Lateral Sclerosis	Siddique, T. et al. (Neurogenetics, 1998) and 8 others Siddique, T. et al. (Neurogenetics, 1998), Pedersen, W. A. et al. (J Neurochem, 2000), Li, Y. J. et al. (Neurogenetics, 2004), Jawaid, A. et al. (Eur J Neurol, 2011), Praline, J. et al. (Eur J Neurol, 2011), Butovsky, O. et al. (Ann Neurol, 2015), Chio, A. et al. (JAMA Neurol, 2016), Mui, S. et al. (Ann Neurol, 1995), Buee, L. et al. (Acta Neuropathol, 1996)
Apolipoprotein E	Apoe	P02650	Amyotrophic Lateral Sclerosis	Siddique, T. et al. (Neurogenetics, 1998) and 8 others Siddique, T. et al. (Neurogenetics, 1998), Pedersen, W. A. et al. (J Neurochem, 2000), Li, Y. J. et al. (Neurogenetics, 2004), Jawaid, A. et al. (Eur J Neurol, 2011), Praline, J. et al. (Eur J Neurol, 2011), Butovsky, O. et al. (Ann Neurol, 2015), Chio, A. et al. (JAMA Neurol, 2016), Mui, S. et al. (Ann Neurol, 1995), Buee, L. et al. (Acta Neuropathol, 1996)
C-X-C motif chemokine 10	Cxcl10	P48973	Amyotrophic Lateral Sclerosis	Ismail, A. et al. (J Neurol Neurosurg Psychiatry, 2013)
Catalase	Cat	P24270	Amyotrophic Lateral Sclerosis	Conforti, F. L. et al. (Neurology, 2012) and 2 others Conforti, F. L. et al. (Neurology, 2012), Pehar, M. et al. (PLoS One, 2014), Parboosingh, J. S. et al. (Neuromuscul Disord, 1995)
Superoxide dismutase [Mn], mitochondrial	Sod2	P07895	Amyotrophic Lateral Sclerosis	Chung, Y. H. et al. (Brain Res, 2003) and 3 others Chung, Y. H. et al. (Brain Res, 2003), Zimmerman, M. C. et al. (J Neurochem, 2007), Blaauwgeers, H. G. et al. (J Neurol Sci, 1996), Shibata, N. et al. (Dev Neurosci, 1996)
Thy-1 cell surface antigen	THY1	M3Y2B1	Amyotrophic Lateral Sclerosis	Wootz, H. et al. (Exp Cell Res, 2006) and 2 others Wootz, H. et al. (Exp Cell Res, 2006), Ezzi, S. A. et al. (J Neurochem, 2010), Wang, Y. et al. (Mol Neurodegener, 2011)
Interleukin-4	Il4	P20096	Amyotrophic Lateral Sclerosis	Shao, H. et al. (Mol Biosyst, 2013)
Beta-hexosaminidase subunit alpha	Hexa	P29416	Amyotrophic Lateral Sclerosis	Goodman, A. B. (Schizophr Bull, 1994)
Beta-hexosaminidase subunit alpha	Hexa	Q641X3	Amyotrophic Lateral Sclerosis	Goodman, A. B. (Schizophr Bull, 1994)
Profilin-1	Pfn1	P62962	Amyotrophic Lateral Sclerosis	Wu, C. H. et al. (Nature, 2012) and 21 others Wu, C. H. et al. (Nature, 2012), Baloh, R. H. (Curr Opin Neurol, 2012), Daoud, H. et al. (Neurobiol Aging, 2013), Tiloca, C. et al. (Neurobiol Aging, 2013), Ingre, C. et al. (Neurobiol Aging, 2013), Lattante, S. et al. (Neurobiol Aging, 2013), Dillen, L. et al. (Neurobiol Aging, 2013), Zou, Z. Y. et al. (Neurobiol Aging, 2013), Chen, Y. et al. (Neurobiol Aging, 2013), Yang, S. et al. (Neurobiol Aging, 2013), Fratta, P. et al. (J Neurol Neurosurg Psychiatry, 2014), Figley, M. D. et al. (J Neurosci, 2014), Syriani, E. et al. (J Neurol, 2014), Smith, B. N. et al. (Neurobiol Aging, 2015), Boopathy, S. et al. (Proc Natl Acad Sci U S A, 2015), Del Poggetto, E. et al. (ACS Chem Biol, 2015), Del Poggetto, E. et al. (Sci Rep, 2015), Brettle, M. et al. (Neurosci Lett, 2015), Freischmidt, A. et al. (BMC Neurosci, 2015), Tanaka, Y. et al. (Hum Mol Genet, 2016), Santamaria, N. et al. (Cell Mol Life Sci, 2017), Lim, L. et al. (Biochim Biophys Acta Biomembr, 2017)
Profilin-1	Pfn1	P62963	Amyotrophic Lateral Sclerosis	Wu, C. H. et al. (Nature, 2012) and 21 others Wu, C. H. et al. (Nature, 2012), Baloh, R. H. (Curr Opin Neurol, 2012), Daoud, H. et al. (Neurobiol Aging, 2013), Tiloca, C. et al. (Neurobiol Aging, 2013), Ingre, C. et al. (Neurobiol Aging, 2013), Lattante, S. et al. (Neurobiol Aging, 2013), Dillen, L. et al. (Neurobiol Aging, 2013), Zou, Z. Y. et al. (Neurobiol Aging, 2013), Chen, Y. et al. (Neurobiol Aging, 2013), Yang, S. et al. (Neurobiol Aging, 2013), Fratta, P. et al. (J Neurol Neurosurg Psychiatry, 2014), Figley, M. D. et al. (J Neurosci, 2014), Syriani, E. et al. (J Neurol, 2014), Smith, B. N. et al. (Neurobiol Aging, 2015), Boopathy, S. et al. (Proc Natl Acad Sci U S A, 2015), Del Poggetto, E. et al. (ACS Chem Biol, 2015), Del Poggetto, E. et al. (Sci Rep, 2015), Brettle, M. et al. (Neurosci Lett, 2015), Freischmidt, A. et al. (BMC Neurosci, 2015), Tanaka, Y. et al. (Hum Mol Genet, 2016), Santamaria, N. et al. (Cell Mol Life Sci, 2017), Lim, L. et al. (Biochim Biophys Acta Biomembr, 2017)
Adenine phosphoribosyltransferase	Aprt	P08030	Amyotrophic Lateral Sclerosis	Lim, M. A. et al. (J Neurosci, 2012), Vergouts, M. et al. (Metab Brain Dis, 2015)
Adenine phosphoribosyltransferase	Aprt	P36972	Amyotrophic Lateral Sclerosis	Lim, M. A. et al. (J Neurosci, 2012), Vergouts, M. et al. (Metab Brain Dis, 2015)
Tumor necrosis factor receptor superfamily member 16	Ngfr	P07174	Amyotrophic Lateral Sclerosis	Seeburger, J. L. et al. (Brain Res, 1993)
Monocyte differentiation antigen CD14	Cd14	P10810	Amyotrophic Lateral Sclerosis	Butovsky, O. et al. (J Clin Invest, 2012)
Collagen alpha-2(IV) chain	Col4a2	P08122	Amyotrophic Lateral Sclerosis	Ekegren, T. et al. (Acta Neurol Scand, 1999)
Hepatocyte growth factor receptor	Met	P16056	Amyotrophic Lateral Sclerosis	Kato, S. et al. (Acta Neuropathol, 2003)
Galectin-1	Lgals1	P11762	Amyotrophic Lateral Sclerosis	Chang-Hong, R. et al. (Exp Neurol, 2005), Kobayakawa, Y. et al. (Neuropathol Appl Neurobiol, 2015)
Galectin-1	Lgals1	P16045	Amyotrophic Lateral Sclerosis	Chang-Hong, R. et al. (Exp Neurol, 2005), Kobayakawa, Y. et al. (Neuropathol Appl Neurobiol, 2015)
Polyadenylate-binding protein	Pabpc2	Q62029	Amyotrophic Lateral Sclerosis	McGurk, L. et al. (J Neuropathol Exp Neurol, 2014)
C-C motif chemokine 2	Ccl2	P10148	Amyotrophic Lateral Sclerosis	Wilms, H. et al. (J Neuroimmunol, 2003) and 5 others Wilms, H. et al. (J Neuroimmunol, 2003), Mitchell, R. M. et al. (Muscle Nerve, 2010), Gupta, P. K. et al. (J Neuroinflammation, 2011), Chan-Il, C. et al. (Cell Transplant, 2013), Gupta, P. K. et al. (PLoS One, 2012), Caioli, S. et al. (Neuropharmacology, 2013)
Delta-aminolevulinic acid dehydratase	Alad	P10518	Amyotrophic Lateral Sclerosis	Kamel, F. et al. (Environ Health Perspect, 2003) and 2 others Kamel, F. et al. (Environ Health Perspect, 2003), Kamel, F. et al. (Neurodegener Dis, 2005), Fang, F. et al. (Am J Epidemiol, 2010)
Glial fibrillary acidic protein	Gfap	P03995	Amyotrophic Lateral Sclerosis	Bendotti, C. et al. (J Neurochem, 2001) and 9 others Bendotti, C. et al. (J Neurochem, 2001), Wootz, H. et al. (Neuroscience, 2006), McLean, J. et al. (J Neurochem, 2008), Xiao, S. et al. (J Neurosci, 2008), Shibata, N. et al. (Neuropathology, 2008), Vargas, M. R. et al. (J Neurosci, 2008), Lee, J. et al. (FASEB J, 2009), Yoshii, Y. et al. (Neurosci Res, 2011), Chen, Y. et al. (Biochem Biophys Res Commun, 2012), McLean, J. R. et al. (Exp Neurol, 2014)
Matrix metalloproteinase-9	Mmp9	P41245	Amyotrophic Lateral Sclerosis	Demestre, M. et al. (J Neuroimmunol, 2005) and 2 others Demestre, M. et al. (J Neuroimmunol, 2005), Kiaei, M. et al. (Exp Neurol, 2007), He, X. et al. (PLoS One, 2013)
Metalloproteinase inhibitor 2	Timp2	P25785	Amyotrophic Lateral Sclerosis	Lorenzl, S. et al. (Neurochem Int, 2003)

Apolipoprotein E

Apoe

Siddique, T. et al. (Neurogenetics, 1998) and 8 others

Siddique, T. et al. (Neurogenetics, 1998), Pedersen, W. A. et al. (J Neurochem, 2000), Li, Y. J. et al. (Neurogenetics, 2004), Jawaid, A. et al. (Eur J Neurol, 2011), Praline, J. et al. (Eur J Neurol, 2011), Butovsky, O. et al. (Ann Neurol, 2015), Chio, A. et al. (JAMA Neurol, 2016), Mui, S. et al. (Ann Neurol, 1995), Buee, L. et al. (Acta Neuropathol, 1996)

Apolipoprotein E

Apoe

P02650

Amyotrophic Lateral Sclerosis

Siddique, T. et al. (Neurogenetics, 1998) and 8 others

Siddique, T. et al. (Neurogenetics, 1998), Pedersen, W. A. et al. (J Neurochem, 2000), Li, Y. J. et al. (Neurogenetics, 2004), Jawaid, A. et al. (Eur J Neurol, 2011), Praline, J. et al. (Eur J Neurol, 2011), Butovsky, O. et al. (Ann Neurol, 2015), Chio, A. et al. (JAMA Neurol, 2016), Mui, S. et al. (Ann Neurol, 1995), Buee, L. et al. (Acta Neuropathol, 1996)

C-X-C motif chemokine 10

Cxcl10