|
Cystatin-C
|
Cst3 |
P21460 |
Alzheimer Disease, Early Onset
|
Bertram, L. et al. (Nat Genet, 2007), Mi, W. et al. (Nat Genet, 2007)
|
|
Interleukin-1 alpha
|
Il1a |
P16598 |
Alzheimer Disease, Early Onset
|
Li, B. H. et al. (J Neural Transm (Vienna), 2013)
|
|
Apolipoprotein E
|
Apoe |
P08226 |
Alzheimer Disease, Early Onset
|
Yasuda, M. et al. (J Neurol Neurosurg Psychiatry, 1999), Feuk, L. et al. (Hum Genet, 2000), Dermaut, B. et al. (Am J Hum Genet, 2002), Lleo, A. et al. (Arch Neurol, 2002), Brickell, K. L. et al. (Arch Neurol, 2006), van der Vlies, A. E. et al. (Psychol Med, 2009), Harold, D. et al. (Nat Genet, 2009), Cellini, E. et al. (Arch Neurol, 2009), Panizzon, M. S. et al. (Neurology, 2010), van der Flier, W. M. et al. (Lancet Neurol, 2011), Balasa, M. et al. (Neurology, 2011), Lambert, J. C. et al. (Nat Genet, 2013), Richardson, J. R. et al. (JAMA Neurol, 2014), Jaunmuktane, Z. et al. (Nature, 2015), Yoon, B. et al. (J Alzheimers Dis, 2016), De Luca, V. et al. (Eur Arch Psychiatry Clin Neurosci, 2016), Levy-Lahad, E. et al. (Ann Neurol, 1995), van Duijn, C. M. et al. (BMJ, 1995), van Duijn, C. M. et al. (Ann Neurol, 1995), van Duijn, C. M. et al. (Nat Genet, 1994), Corder, E. H. et al. (Science, 1993), Egensperger, R. et al. (Acta Neuropathol, 1995), Bronzova, J. et al. (J Neurol, 1996), Lendon, C. L. et al. (Hum Mutat, 1997), Scott, W. K. et al. (Ann Neurol, 1997)
|
|
Apolipoprotein E
|
Apoe |
P02650 |
Alzheimer Disease, Early Onset
|
Yasuda, M. et al. (J Neurol Neurosurg Psychiatry, 1999), Feuk, L. et al. (Hum Genet, 2000), Dermaut, B. et al. (Am J Hum Genet, 2002), Lleo, A. et al. (Arch Neurol, 2002), Brickell, K. L. et al. (Arch Neurol, 2006), van der Vlies, A. E. et al. (Psychol Med, 2009), Harold, D. et al. (Nat Genet, 2009), Cellini, E. et al. (Arch Neurol, 2009), Panizzon, M. S. et al. (Neurology, 2010), van der Flier, W. M. et al. (Lancet Neurol, 2011), Balasa, M. et al. (Neurology, 2011), Lambert, J. C. et al. (Nat Genet, 2013), Richardson, J. R. et al. (JAMA Neurol, 2014), Jaunmuktane, Z. et al. (Nature, 2015), Yoon, B. et al. (J Alzheimers Dis, 2016), De Luca, V. et al. (Eur Arch Psychiatry Clin Neurosci, 2016), Levy-Lahad, E. et al. (Ann Neurol, 1995), van Duijn, C. M. et al. (BMJ, 1995), van Duijn, C. M. et al. (Ann Neurol, 1995), van Duijn, C. M. et al. (Nat Genet, 1994), Corder, E. H. et al. (Science, 1993), Egensperger, R. et al. (Acta Neuropathol, 1995), Bronzova, J. et al. (J Neurol, 1996), Lendon, C. L. et al. (Hum Mutat, 1997), Scott, W. K. et al. (Ann Neurol, 1997)
|
|
Superoxide dismutase [Mn], mitochondrial
|
Sod2 |
P07895 |
Alzheimer Disease, Early Onset
|
Reed, T. T. et al. (Brain Res, 2009)
|
|
Insulin-degrading enzyme
|
Ide |
Q9JHR7 |
Alzheimer Disease, Early Onset
|
Bertram, L. et al. (Nat Genet, 2007)
|
|
Insulin-degrading enzyme
|
Ide |
P35559 |
Alzheimer Disease, Early Onset
|
Bertram, L. et al. (Nat Genet, 2007)
|
|
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
|
Plcg2 |
Q8CIH5 |
Alzheimer Disease, Early Onset
|
Sims, R. et al. (Nat Genet, 2017)
|
|
Brain-derived neurotrophic factor
|
Bdnf |
P21237 |
Alzheimer Disease, Early Onset
|
Garzon, D. J. et al. (J Neurosci, 2007)
|
|
Alpha-L-iduronidase
|
Idua |
P48441 |
Alzheimer Disease, Early Onset
|
Schapansky, J. et al. (Exp Neurol, 2007)
|
|
Thimet oligopeptidase
|
Thop1 |
Q8C1A5 |
Alzheimer Disease, Early Onset
|
De Strooper, B. et al. (Cold Spring Harb Perspect Med, 2012)
|
|
Thimet oligopeptidase
|
Thop1 |
P24155 |
Alzheimer Disease, Early Onset
|
De Strooper, B. et al. (Cold Spring Harb Perspect Med, 2012)
|
|
Reelin
|
Reln |
P58751 |
Alzheimer Disease, Early Onset
|
Kocherhans, S. et al. (J Neurosci, 2010)
|
|
Macrophage-expressed gene 1 protein
|
Mpeg1 |
A1L314 |
Alzheimer Disease, Early Onset
|
Schapansky, J. et al. (Exp Neurol, 2007)
|
|
5'-3' exonuclease PLD3
|
Pld3 |
Q5FVH2 |
Alzheimer Disease, Early Onset
|
Cacace, R. et al. (Hum Mutat, 2015)
|
|
Triggering receptor expressed on myeloid cells 2
|
Trem2 |
Q99NH8 |
Alzheimer Disease, Early Onset
|
Pottier, C. et al. (J Alzheimers Dis, 2013), Abduljaleel, Z. et al. (PLoS One, 2014), Slattery, C. F. et al. (Alzheimers Dement, 2014), Sims, R. et al. (Nat Genet, 2017)
|
|
Nascent polypeptide-associated complex subunit alpha, muscle-specific form
|
Naca |
P70670 |
Alzheimer's Disease
|
Kim, S. H. et al. (J Investig Med, 2002)
|
|
Nascent polypeptide-associated complex subunit alpha
|
Naca |
Q60817 |
Alzheimer's Disease
|
Kim, S. H. et al. (J Investig Med, 2002)
|
|
Membrane-associated progesterone receptor component 1
|
Pgrmc1 |
P70580 |
Alzheimer's Disease
|
Izzo, N. J. et al. (PLoS One, 2014)
|
|
Phosphomannomutase 2
|
Pmm2 |
Q9Z2M7 |
Alzheimer's Disease
|
Lukiw, W. J. et al. (J Neurosci Res, 1997)
|
|
Low-density lipoprotein receptor-related protein 6
|
Lrp6 |
O88572 |
Alzheimer's Disease
|
De Ferrari, G. V. et al. (Proc Natl Acad Sci U S A, 2007), Alarcon, M. A. et al. (Neurobiol Aging, 2013)
|
|
C1q-related factor
|
C1ql1 |
O88992 |
Alzheimer's Disease
|
Guo, Q. et al. (Neurobiol Aging, 2012)
|
|
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial
|
Ndufb8 |
Q9D6J5 |
Alzheimer's Disease
|
Francis, B. M. et al. (J Alzheimers Dis, 2014)
|
|
Superoxide dismutase [Cu-Zn]
|
Sod1 |
P08228 |
Alzheimer's Disease
|
Kisby, G. E. et al. (Drug Metab Rev, 1999), Ihara, Y. et al. (Acta Neurol Scand, 2000), Yasojima, K. et al. (Neurology, 2001), Harris-Cerruti, C. et al. (Eur J Neurosci, 2004), Rachakonda, V. et al. (Cell Res, 2004), Grunblatt, E. et al. (Neurobiol Aging, 2005), Koh, S. H. et al. (Eur J Neurosci, 2005), Boll, M. C. et al. (Neurochem Res, 2008), Somerville, M. J. et al. (Brain Res Mol Brain Res, 1991), Yoon, E. J. et al. (Exp Mol Med, 2009), Babich, P. S. et al. (Bull Exp Biol Med, 2009), Gagliardi, S. et al. (Neurobiol Dis, 2010), Guo, Y. et al. (Brain Res, 2011), Murakami, K. et al. (J Biol Chem, 2011), Cashman, J. R. et al. (Neurodegener Dis, 2012), Ghani, M. et al. (Neurobiol Aging, 2015), Mota, S. I. et al. (Biochim Biophys Acta, 2015), Adams, H. H. et al. (Alzheimers Dement, 2015), Paillusson, S. et al. (Trends Neurosci, 2016), Zubenko, G. S. et al. (Biol Psychiatry, 1989), Fujii, J. et al. (Nephrol Dial Transplant, 1996)
|
|
Ceruloplasmin
|
Cp |
P13635 |
Alzheimer's Disease
|
Squitti, R. et al. (J Neural Transm (Vienna), 2007), Capo, C. R. et al. (Biometals, 2008), Boll, M. C. et al. (Neurochem Res, 2008), Zappasodi, F. et al. (Brain Res, 2008), Squitti, R. et al. (Prion, 2008), Squitti, R. et al. (J Alzheimers Dis, 2011), Squitti, R. et al. (Rejuvenation Res, 2013), Squitti, R. et al. (Curr Alzheimer Res, 2013), Lahiri, D. K. et al. (BMC Genomics, 2013), Squitti, R. et al. (Neuromolecular Med, 2013), Barbariga, M. et al. (J Biol Chem, 2014), Siotto, M. et al. (J Alzheimers Dis, 2016)
|